Pathogenesis: understanding the disease: Cell growth

Research must specifically focus on breast cancer tumor and stromal biology, including: (1) studies of relevant proteins and genes with an emphasis on their relationship to the actual disease, and (2) elucidating key cell signaling, growth control, cell c


Understanding HER3 and mTor Signaling in Breast Cancer 2012 (Cycle 18)
  University of California, San Francisco   $100,000
  Award Type: IDEA
 
The Role of microRNAs in Triple-Negative Breast Cancer 2010 (Cycle 16)
  University of California, San Francisco   $89,200
  Award Type: Postdoctoral Fellowship
 
Targeting MYC in Human Breast Cancer 2009 (Cycle 15)
  University of California, San Francisco   $90,000
  Award Type: Postdoctoral Fellowship
 
Novel Akt Regulatory Factor PHLPP in Breast Cancer 2009 (Cycle 15)
  University of California, San Diego   $0
  Award Type: Dissertation
 
The Role of Estrogen Receptor in Endocrine Resistance 2009 (Cycle 15)
  Beckman Research Institute of the City of Hope   $76,000
  Award Type: Dissertation
 
The Role of EGF Variant mLEEK and Grp78 in Breast Cancer 2009 (Cycle 15)
  Stanford University   $241,380
  Award Type: IDEA
 
Indole (I3C) Control of Breast Cancer by ER Downregulation 2007 (Cycle 13)
  University of California, Berkeley   $76,000
  Award Type: Dissertation
 
Lipid Raft Composition in Deregulated ERBB2 Signaling 2007 (Cycle 13)
  University of California, Los Angeles   $99,371
  Award Type: IDEA
 
A New Mouse Model of PI3-Kinase Induced Breast Cancer 2007 (Cycle 13)
  University of California, San Francisco   $89,600
  Award Type: Postdoctoral Fellowship
 
Modeling, Targeting Acetyl-CoA Metabolism in Breast Cancer 2006 (Cycle 12)
  The Burnham Institute for Medical Research   $90,000
  Award Type: Postdoctoral Fellowship
 
Inflammation Alters Transcription by ER in Breast Cancer 2006 (Cycle 12)
  University of California, San Diego   $75,051
  Award Type: Dissertation
 
The Role of Estrogen-Related Receptors in Breast Cancer 2006 (Cycle 12)
  Scripps Research Institute   $278,106
  Award Type: IDEA
 
The Role of Chk1 in Breast Cancer DNA Damage Repair 2006 (Cycle 12)
  Scripps Research Institute   $80,740
  Award Type: Postdoctoral Fellowship
 
Profiling Drug Metabolism (P450) Proteins in Breast Cancer 2006 (Cycle 12)
  Scripps Research Institute   $105,147
  Award Type: Postdoctoral Fellowship
 
Breast Cancer Studies in a 3-D Cell Culture System 2005 (Cycle 11)
  The Burnham Institute for Medical Research   $188,602
  Award Type: IDEA
 
Evaluating the Role of the RIN1 Gene in Breast Cancer 2005 (Cycle 11)
  University of California, Los Angeles   $71,835
  Award Type: Dissertation
 
A Role for p53 and Splicing Factor SAP145 in Breast Cancer 2005 (Cycle 11)
  University of California, Irvine   $76,000
  Award Type: Dissertation
 
Role of BI-1 Protein in Breast Cancer Apoptosis 2004 (Cycle 10)
  The Burnham Institute for Medical Research   $87,424
  Award Type: Postdoctoral Fellowship
 
Oxidative Stress and Estrogen Receptor Structural Changes 2004 (Cycle 10)
  Buck Institute for Age Research   $1,122,520
  Award Type: SPRC Full
 
Maspin: Breast Cancer Suppression through Enzyme Inhibition? 2004 (Cycle 10)
  The Burnham Institute for Medical Research   $196,115
  Award Type: STEP
 
A Novel Approach to Inactivate the Estrogen Receptor 2004 (Cycle 10)
  University of California, San Francisco   $60,000
  Award Type: Dissertation
 
Src Signaling in Breast Cancer 2003 (Cycle IX)
  University of California, Berkeley   $75,000
  Award Type: IDEA
 
Understanding Herceptin Resistance with Dual Function Array 2003 (Cycle IX)
  University of California, San Francisco   $49,612
  Award Type: Postdoctoral Fellowship
 
Study of the Apoptotic Phenotype as a Hallmark of Malignancy 2003 (Cycle IX)
  University of California, San Francisco   $155,099
  Award Type: Career Enrichment
 
Overcoming Tamoxifen-resistance in Breast Cancer 2003 (Cycle IX)
  The Burnham Institute for Medical Research   $281,370
  Award Type: STEP
 
Cell-Killing Effect of Orphan Receptor TR3 in Breast Cancer 2002 (Cycle VIII)
  The Burnham Institute for Medical Research   $84,643
  Award Type: Postdoctoral Fellowship
 
Structure and Function of the Bax Apoptosis Regulator 2002 (Cycle VIII)
  The Burnham Institute for Medical Research   $285,141
  Award Type: STEP
 
Potential Role of a Novel Repressor Complex in Breast Cancer 2002 (Cycle VIII)
  University of California, San Diego   $0
  Award Type: Postdoctoral Fellowship
 
Regulation of Estrogen Response by Corepressors 2002 (Cycle VIII)
  University of California, Davis   $149,942
  Award Type: STEP
 
Analysis of EGFR Transcript Splicing in C. Elegans 2002 (Cycle VIII)
  California Institute of Technology   $86,400
  Award Type: Postdoctoral Fellowship
 
Cyclin E Affects Growth Arrest in Breast Cancer Cells 2002 (Cycle VIII)
  University of California, Davis   $50,386
  Award Type: Dissertation
 
Role of Pak Kinase in Breast Cancer Cell Cycle Progression 2002 (Cycle VIII)
  Scripps Research Institute   $86,400
  Award Type: Postdoctoral Fellowship
 
Novel Ligands as Probes of Estrogen Receptor Signaling 2002 (Cycle VIII)
  University of California, San Francisco   $50,941
  Award Type: Dissertation
 
A Novel Anti-estrogen Resistance Mechanism in Breast Cancer 2002 (Cycle VIII)
  The Burnham Institute for Medical Research   $143,250
  Award Type: IDEA
 
The Role of SGK in Breast Cancer Proliferation 2001 (Cycle VII)
  Scripps Research Institute   $85,212
  Award Type: Postdoctoral Fellowship
 
Genetic Analysis of ErbB Signaling in C. Elegans 2001 (Cycle VII)
  California Institute of Technology   $85,633
  Award Type: Postdoctoral Fellowship
 
Molecular Study of BAG Domains: A New Motif in Breast Cancer 2001 (Cycle VII)
  The Burnham Institute for Medical Research   $49,869
  Award Type: Postdoctoral Fellowship
 
Molecular Characterization of ErbB2 Positive Breast Cancers 2001 (Cycle VII)
  Buck Institute for Age Research   $86,200
  Award Type: Postdoctoral Fellowship
 
SBP-1: A Novel Survivin Binding Protein in Breast Cancer 2001 (Cycle VII)
  The Burnham Institute for Medical Research   $32,050
  Award Type: Postdoctoral Fellowship
 
P132Cas and Antiestrogen Resistance of Breast Cancer 2001 (Cycle VII)
  The Burnham Institute for Medical Research   $42,660
  Award Type: Postdoctoral Fellowship
 
Cell Growth Control of Breast Epithelial Cells 2000 (Cycle VI)
  Scripps Research Institute   $265,950
  Award Type: IDEAS II
 
Anti-E-Cadherin Apoptosis of Inflammatory Breast Carcinoma 2000 (Cycle VI)
  University of California, Los Angeles   $80,000
  Award Type: Postdoctoral Fellowship
 
A Novel Signal Transduction Pathway in Breast Cancer 2000 (Cycle VI)
  University of California, San Diego   $79,981
  Award Type: Postdoctoral Fellowship
 
The Role of the BMK1-MEKK3 Pathway in Breast Cancer 2000 (Cycle VI)
  Scripps Research Institute   $64,152
  Award Type: Postdoctoral Fellowship
 
The Control of Breast Cancer Cell Death 2000 (Cycle VI)
  Stanford University   $306,149
  Award Type: IDEAS II
 
Novel Mechanisms of ErbB-2-Mediated Breast Cancer Metastasis 2000 (Cycle VI)
  Scripps Research Institute   $257,006
  Award Type: New Investigator
 
Studies on the Role of the ER-beta in Breast Cancer 2000 (Cycle VI)
  Lawrence Berkeley National Laboratory   $59,102
  Award Type: Postdoctoral Fellowship
 
GATA-3 Expression in Hormone Responsive Breast Cancer 1999 (Cycle V)
  Stanford University   $232,444
  Award Type: IDEAS II
 
COX-2 and Apoptosis Regulation in Breast Cancer 1999 (Cycle V)
  The Burnham Institute for Medical Research   $75,596
  Award Type: Postdoctoral Fellowship
 
The Regulation of p53 Activity in Breast Cancer 1999 (Cycle V)
  University of California, San Diego   $51,393
  Award Type: IDEAS II
 
Role of the EphB4 Receptor Tyrosine Kinase in Breast Cancer 1999 (Cycle V)
  The Burnham Institute for Medical Research   $389,758
  Award Type: IDEAS II
 
Specificity of Ras Signaling in Breast Cancer 1999 (Cycle V)
  Scripps Research Institute   $236,706
  Award Type: IDEAS II
 
Novel Binding Functions of Mutant p53 in Breast Cancer Cells 1998 (Cycle IV)
  Lawrence Berkeley National Laboratory   $68,889
  Award Type: Postdoctoral Fellowship
 
The Role of a Newly Discovered Neuregulin in Breast Cancer 1998 (Cycle IV)
  Scripps Research Institute   $87,472
  Award Type: IDEA
 
Role of Rb Protein and Cell Cycle Defects in Breast Cancer 1998 (Cycle IV)
  The Burnham Institute for Medical Research   $283,376
  Award Type: IDEAS II
 
A Novel Drug Induces Apoptosis in Breast Cancer Cells 1998 (Cycle IV)
  Stanford University   $228,595
  Award Type: IDEAS II
 
Disruption of Cyclin E/Cell Cycle In Breast Cancer Cells 1997 (Cycle III)
  Scripps Research Institute   $75,600
  Award Type: Postdoctoral Fellowship
 
Regulation of Wnt: Clues for breast cancer pathognesis 1997 (Cycle III)
  University of California, Irvine   $13,849
  Award Type: Postdoctoral Fellowship
 
TRAF-regulated Signal Transduction in Breast Cancer 1997 (Cycle III)
  The Burnham Institute for Medical Research   $75,600
  Award Type: Postdoctoral Fellowship
 
Fate Mapping of Progesterone Receptor Positive Breast Cells 1997 (Cycle III)
  Lawrence Berkeley National Laboratory   $243,380
  Award Type: IDEA
 
Growth Factor Receptor Activation in Breast Cancer 1997 (Cycle III)
  Scripps Research Institute   $267,291
  Award Type: IDEA
 
The Role of a Novel Estrogen Receptor in Breast Cancer 1997 (Cycle III)
  Lawrence Berkeley National Laboratory   $231,039
  Award Type: IDEA
 
Hormonal Control of HER2neu and BRCA1 in Breast Cancer 1997 (Cycle III)
  Sidney Kimmel Cancer Center   $286,676
  Award Type: IDEA
 
Molecular mechanisms of EGF receptor endocytosis 1996 (Cycle II)
  University of California, San Diego   $69,685
  Award Type: Postdoctoral Fellowship
 
Why Does Normal Cell Death Not Occur in Breast Cancer? 1996 (Cycle II)
  University of California, San Diego   $38,088
  Award Type: Postdoctoral Fellowship
 
Novel Ways to Control the Growth of Mammary Epithelial Cells 1996 (Cycle II)
  Scripps Research Institute   $35,256
  Award Type: Postdoctoral Fellowship
 
Loss of Tumor Suppressor Proteins in Breast Cancer Cells 1996 (Cycle II)
  Lawrence Berkeley National Laboratory   $69,605
  Award Type: Postdoctoral Fellowship
 
Estrogen receptor-interacting proteins in breast cancer 1996 (Cycle II)
  University of Southern California   $492,719
  Award Type: Research Project
 
Nongenomic actions of antiestrogens 1996 (Cycle II)
  John Wayne Cancer Institute   $495,150
  Award Type: Research Project
 
Immune responses to breast cancers: function of TRAF protein 1996 (Cycle II)
  The Burnham Institute for Medical Research   $284,581
  Award Type: Research Project
 
Enhanced lysosomal degradation of growth factor receptors 1996 (Cycle II)
  University of California, San Diego   $295,246
  Award Type: Research Project
 
Growth Factor Control of Breast Tumor Cell Proliferation 1995 (Cycle I)
  University of California, San Diego   $35,000
  Award Type: Postdoctoral Fellowship
 
Estrogen Receptor Regulation in Breast Cancer 1995 (Cycle I)
  Stanford University   $75,238
  Award Type: Postdoctoral Fellowship
 
Isolation of Estrogen Receptor Cofactors fron Breast Tumors 1995 (Cycle I)
  University of California, San Diego   $68,607
  Award Type: Postdoctoral Fellowship
 
Changes in Transport into the Nucleus in Breast Cancer 1995 (Cycle I)
  Scripps Research Institute   $5,047
  Award Type: Postdoctoral Fellowship
 
Progesterone Action in Human Breast Cancer 1995 (Cycle I)
  Lawrence Berkeley National Laboratory   $85,733
  Award Type: IDEA
 
Regulatory Mechanisms for Growth & Motility in Breast Cancer 1995 (Cycle I)
  Scripps Research Institute   $82,900
  Award Type: IDEA
 
Loss of p53 Tumor Suppressor Function in Breast Cancer 1995 (Cycle I)
  City of Hope National Medical Center   $313,848
  Award Type: New Investigator
 
ErbB2 and Control of Growth in Breast Cancer Cells 1995 (Cycle I)
  University of California, San Diego   $144,936
  Award Type: New Investigator
 
Control of Estrogen Production in Breast Cancer 1995 (Cycle I)
  Beckman Research Institute of the City of Hope   $342,712
  Award Type: Research Project
 
Regaining Control over Breast Cancer Cells 1995 (Cycle I)
  University of California, San Diego   $270,132
  Award Type: Research Project
 
Mechanisms of Aberrant Cell Growth in Breast Cancer 1995 (Cycle I)
  University of California, San Diego   $276,643
  Award Type: Research Project