Innovative Treatment Modalities: search for a cure: Gene therapy & other treatments

Promising leads from biology-based studies are encouraged to begin the critical path to clinical translation. Examples include immunotherapy, delivery technologies, gene therapy, new drug development/testing, and new approaches to clinical decision-making


Intranasal drug delivery for brain metastatic breast cancer 2013 (Cycle 19)
  University of Southern California   $242,530
  Award Type: IDEA
 
Radiation-Induced Migration of Breast Cancer Cells 2013 (Cycle 19)
  Stanford University   $237,295
  Award Type: IDEA
 
Using Epigenetic Changes to Stratify DCIS Biopsies 2012 (Cycle 18)
  University of California, San Francisco   $750,000
  Award Type: Translational Research
 
Host Hypoxia to Treat Breast Cancer Brain Metastasis 2012 (Cycle 18)
  Scripps Research Institute   $284,250
  Award Type: IDEA
 
Reducing Surgical Morbidity of Breast Cancer Staging 2011 (Cycle 17)
  Beckman Research Institute of the City of Hope   $469,769
  Award Type: IDEA-competitive renewal
 
Vitamin D and Breast Cancer in Obesity: Therapeutic Trials 2011 (Cycle 17)
  Stanford University   $1,166,615
  Award Type: Translational Research
 
Targeting Brain Metastasis with a Cell-based Approach 2010 (Cycle 16)
  Scripps Research Institute   $284,354
  Award Type: IDEA
 
Measuring Real-World Breast Cancer Outcomes 2010 (Cycle 16)
  Stanford University   $1,066,225
  Award Type: Translational Research
 
6th Symposium on the Intraductal Approach to Breast Cancer 2009 (Cycle 15)
  Dr. Susan Love Research Foundation   $25,000
  Award Type: Joining Forces
 
Antibody-based Targeting of Breast Cancer Stem Cells 2009 (Cycle 15)
  University of California, Santa Barbara   $150,000
  Award Type: IDEA
 
Modulation of Breast Cancer Stem Cell Response to Radiation 2009 (Cycle 15)
  University of California, Los Angeles   $250,000
  Award Type: IDEA-competitive renewal
 
Reducing Surgical Morbidity of Breast Cancer Staging 2009 (Cycle 15)
  University of California, Davis   $149,983
  Award Type: IDEA
 
Survival in de novo and Recurrent Metastatic Breast Cancer 2009 (Cycle 15)
  Beckman Research Institute of the City of Hope   $249,000
  Award Type: IDEA
 
Metabolite Imaging to Identify Drug Resistant Breast Cancer 2009 (Cycle 15)
  Lawrence Berkeley National Laboratory   $171,892
  Award Type: IDEA
 
Breast Cancer Treatment Monitoring Combining MRI and Optics 2007 (Cycle 13)
  University of California, San Francisco   $113,166
  Award Type: IDEA
 
Modulation of Breast Cancer Stem Cell Response to Radiation 2007 (Cycle 13)
  University of California, Los Angeles   $149,377
  Award Type: IDEA
 
Neural Stem Cell Therapy for Breast Cancer Brain Metastases 2007 (Cycle 13)
  Scripps Research Institute   $419,400
  Award Type: IDEA-competitive renewal
 
Intraductal Therapy of DCIS: A Presurgery Study 2007 (Cycle 13)
  Dr. Susan Love Research Foundation   $851,559
  Award Type: Translational Research
 
Real-Time 3D Ultrasound Image-Guidance for Breast Surgery 2006 (Cycle 12)
  Stanford University   $66,141
  Award Type: Dissertation
 
Intraoperative Assessment of Surgical Lumpectomy Margins 2006 (Cycle 12)
  John Wayne Cancer Institute   $268,810
  Award Type: IDEA
 
Neural Stem Cell Therapy for Breast Cancer Brain Metastases 2006 (Cycle 12)
  Scripps Research Institute   $302,085
  Award Type: IDEA
 
ID4: a Prognostic Factor of Breast Cancer Metastasis 2005 (Cycle 11)
  John Wayne Cancer Institute   $283,200
  Award Type: IDEA
 
Preclinical Trials for Breast Cancer 2003 (Cycle IX)
  University of California, Davis   $25,000
  Award Type: Joining Forces
 
Drug Dose Tailoring Based on Patient-Specific Factors 2002 (Cycle VIII)
  University of California, San Francisco   $11,827
  Award Type: Dissertation
 
Selective Targeting of Breast Cancer with Radioiodide 2001 (Cycle VII)
  Stanford University   $315,200
  Award Type: STEP
 
Herba Scutellaria Barbatae for Metastatic Breast Cancer 2001 (Cycle VII)
  University of California, San Francisco   $232,364
  Award Type: STEP
 
Stress Protein and Drug Resistance in Human Breast Cancer 2000 (Cycle VI)
  University of Southern California   $325,873
  Award Type: IDEAS II
 
Wnt Signaling in Breast Cancer: Translational Studies 2000 (Cycle VI)
  University of California, Irvine   $328,129
  Award Type: TRC Full
 
Chinese Herbal Therapy (CHT) for Symptom Management 2000 (Cycle VI)
  University of California, San Francisco   $200,000
  Award Type: IDEAS II
 
Thrombosis for Anti-angiogenic Therapy of Breast Cancer 2000 (Cycle VI)
  University of California, Irvine   $199,633
  Award Type: IDEAS II
 
Can Molecular Markers Predict Response to Adjuvant Therapy 1999 (Cycle V)
  Kaiser Foundation Research Institute   $260,545
  Award Type: TRC Full
 
Mechanism of Radiosensitivity in Breast Cancer Cells 1999 (Cycle V)
  Scripps Research Institute   $37,200
  Award Type: Postdoctoral Fellowship
 
New Radiation Therapy for HER-2-overexpressing Breast Cancer 1999 (Cycle V)
  University of California, Los Angeles   $200,000
  Award Type: IDEAS II
 
Breast Cancer Gene Expression Using Amplified Core Biopsies 1999 (Cycle V)
  Stanford University   $155,286
  Award Type: IDEAS II
 
Bispecific Antibodies for Radiotherapy of Breast Cancer 1999 (Cycle V)
  University of California, Davis   $68,615
  Award Type: Postdoctoral Fellowship
 
Molecular Mapping of Surgical Margins 1998 (Cycle IV)
  California Pacific Medical Center Research Institute   $287,992
  Award Type: ITaMoCAs
 
Breast Tumor Markers and Response to Adjuvant Therapy 1998 (Cycle IV)
  Kaiser Foundation Research Institute   $77,327
  Award Type: TRC Pilot
 
Timing of Breast Cancer Surgery, Menstrual Cycle & Prognosis 1998 (Cycle IV)
  University of California, San Diego   $506,070
  Award Type: TRC Full
 
Breast Cancer Markers and Response to Adjuvant Therapy 1998 (Cycle IV)
  Kaiser Foundation Research Institute   $0
  Award Type: TRC Pilot
 
Breast Tumor Markers and Response to Adjuvant Therapy 1998 (Cycle IV)
  Kaiser Foundation Research Institute   $0
  Award Type: TRC Pilot
 
Gene Therapy for Breast Cancer 1997 (Cycle III)
  California Pacific Medical Center Research Institute   $293,383
  Award Type: ITaMoCAs
 
Inhibition of Angiogenesis in Breast Cancer 1997 (Cycle III)
  University of California, San Francisco   $67,830
  Award Type: TRC Pilot
 
The Role of Meltrin-a in Breast Cancer-Associated Bone Loss 1997 (Cycle III)
  The Burnham Institute for Medical Research   $75,600
  Award Type: Postdoctoral Fellowship
 
Breast Cancer Gene Therapy Using a Metastasis Inhibitor 1997 (Cycle III)
  University of Southern California   $75,599
  Award Type: Postdoctoral Fellowship
 
Improved delivery of pharmaceuticals to breast cancer 1996 (Cycle II)
  University of California, San Francisco   $145,492
  Award Type: ITaMoCAs
 
Pre-clinical cryosurgery testing in breast cancer treatment 1996 (Cycle II)
  University of California, Berkeley   $200,000
  Award Type: ITaMoCAs
 
Outpatient Stem Cell Transplants for Breast Cancer 1996 (Cycle II)
  University of California, San Diego   $189,970
  Award Type: ITaMoCAs
 
Tibetan Medicine for Advanced Breast Cancer 1996 (Cycle II)
  University of California, San Francisco   $53,231
  Award Type: ITaMoCAs
 
Radiosurgery of early breast cancer 1996 (Cycle II)
  University of Southern California   $76,713
  Award Type: ITaMoCAs
 
Targeted gene therapy using anti-pl85HER2 immunoliposomes 1996 (Cycle II)
  University of California, San Francisco   $205,410
  Award Type: ITaMoCAs
 
Outpatient Stem Cell Transplants for Breast Cancer 1996 (Cycle II)
  Scripps Clinic & Research Foundation   $0
  Award Type: ITaMoCAs
 
Blocking Breast Cancer Progression with Radioactive Antibody 1995 (Cycle I)
  University of California, Irvine   $50,000
  Award Type: IDEA
 
Breast Cancer Chemotherapy: Does It Impair Brain Function? 1995 (Cycle I)
  California School of Professional Psychology   $307,456
  Award Type: New Investigator
 
Investigation of Improved Drug Delivery in Breast Cancer 1995 (Cycle I)
  University of California, Irvine   $292,905
  Award Type: Research Project